Electrode-dependent asymmetric conduction mechanisms in K0.5Na0.5NbO3 micro-capacitors

The ultimate performance of devices employing lead-free piezoelectrics is determined not only by the intrinsic properties of the piezo, but also by processes and materials employed to create the electric contacts. In this paper, we investigate the impact of different metallic electrodes with increasing chemical reactivity (Pt, Ni, Ti, Cr), on the asymmetric behavior of the leakage current in M/K0.5Na0.5NbO3/Pt(111) micro-capacitors, where M stands for the top metallic electrode. For all electrodes we found a marked leakage asymmetry that we ascribed to the presence of a Schottky-like rectifying junction at the M/K0.5Na0.5NbO3/Pt(111) bottom interface, while the corresponding junction at the top interface is deeply affected by the creation of oxygen vacancies due to oxygen scavenging during the growth of the top metallic electrodes, leading to an almost ohmic top contact. The leakage increases with the reactivity of the electrodes, while the asymmetry decreases, thus suggesting that the creation of the top metal/K0.5Na0.5NbO3 interface generates oxygen vacancies diffusing down to the bottom interface and impacting on the rectifying behavior of the Schottky-like junction. Noteworthy, this asymmetric conduction can reflect in an asymmetric piezoelectric and ferroelectric behavior, as a sizable portion of the applied voltage drops across the rectifying junction in reverse bias, thus hampering symmetric bipolar operation, especially in leaky materials

Dissipative Dynamics of Polymer Phononic Materials

Phononic materials are artificial composites with unprecedented abilities to control acoustic waves in solids. Their performance is mainly governed by their architecture, determining frequency ranges in which wave propagation is inhibited. However, the dynamics of phononic materials also depends on the mechanical and material properties of their constituents. In the case of viscoelastic constituents, such as most polymers, it is challenging to correctly predict the actual dynamic behavior of real phononic structures. Existing studies on this topic either lack experimental evidence or are limited to specific materials and architectures in restricted frequency ranges. A general framework is developed and employed to characterize the dynamics of polymer phononic materials with different architectures made of both thermoset and thermoplastic polymers, presenting qualitatively different viscoelastic behaviors. Through a comparison of experimental results with numerical predictions, the reliability of commonly used elastic and viscoelastic material models is evaluated in broad frequency ranges. Correlations between viscous effects and the two main band-gap formation mechanisms in phononic materials are revealed, and experimentally verified guidelines on how to correctly predict their dissipative response are proposed in a computationally efficient way. Overall, this work provides comprehensive guidelines for the extension of phononics modeling to applications involving dissipative viscoelastic materials.</p

Sustained proliferation in cancer: mechanisms and novel therapeutic targets

Proliferation is an important part of cancer development and progression. This is manifest by altered expression and/or activity of cell cycle related proteins. Constitutive activation of many signal transduction pathways also stimulates cell growth. Early steps in tumor development are associated with a fibrogenic response and the development of a hypoxic environment which favors the survival and proliferation of cancer stem cells. Part of the survival strategy of cancer stem cells may manifested by alterations in cell metabolism. Once tumors appear, growth and metastasis may be supported by overproduction of appropriate hormones (in hormonally dependent cancers), by promoting angiogenesis, by undergoing epithelial to mesenchymal transition, by triggering autophagy, and by taking cues from surrounding stromal cells. A number of natural compounds (e.g., curcumin, resveratrol, indole-3-carbinol, brassinin, sulforaphane, epigallocatechin-3-gallate, genistein, ellagitannins, lycopene and quercetin) have been found to inhibit one or more pathways that contribute to proliferation (e.g., hypoxia inducible factor 1, nuclear factor kappa B, phosphoinositide 3 kinase/Akt, insulin-like growth factor receptor 1, Wnt, cell cycle associated proteins, as well as androgen and estrogen receptor signaling). These data, in combination with bioinformatics analyses, will be very important for identifying signaling pathways and molecular targets that may provide early diagnostic markers and/or critical targets for the development of new drugs or drug combinations that block tumor formation and progression

Assessment of Silica Recovery from Metallurgical Mining Waste, by Means of Column Flotation

The generation of mining waste commonly led to the use of spaces for its disposal. Challenges like mitigating the damage to surrounding communities have promoted the need to reuse, recycle and/or reduce their generation. Besides, these residues may become a source of materials, which are capable of being recovered and reused in several industries, minimizing the environmental impact. In the mining region of Pachuca, Mexico, waste from the mining industry have been generated for more than 100 years, which have a high SiO2 content that can be recovered for various industrial applications. This work aims to recover silica from a material of the Dos Carlos dam. A columnar system composed of two-stage of cleaning was used, considering a JLT (surface liquid rate) value of 0.45 and 0.68 cm/s, respectively; while the Jg (surface gas rate) value was 0.30 cm/s for both stages. Similar bubble sizes in the range of Jg 0.10 to 0.30 cm/s, with values between 0.14 and 0.16 cm in the first stage, and 0.05 to 0.06 cm in the second one. This provided a recovery of 75.10% for all the allotropic phases of silica (quartz, trydimite, and cristobalite) leaving a concentration of 24.90% of a feldspathic phase (orthoclase), as flotation tails

VAMOS: A pathfinder for the HAWC gamma-ray observatory

VAMOS1 was a prototype detector built in 2011 at an altitude of 4100 m a.s.l. in the state of Puebla, Mexico. The aim of VAMOS was to finalize the design, construction techniques and data acquisition system of the HAWC observatory. HAWC is an air-shower array currently under construction at the same site of VAMOS with the purpose to study the TeV sky. The VAMOS setup included six water Cherenkov detectors and two different data acquisition systems. It was in operation between October 2011 and May 2012 with an average live time of 30%. Besides the scientific verification purposes, the eight months of data were used to obtain the results presented in this paper: the detector response to the Forbush decrease of March 2012, and the analysis of possible emission, at energies above 30 GeV, for long gamma-ray bursts GRB111016B and GRB120328B